反应条件
n-butyllithium in tetrahydrofuran; hexane under Ar; addn. of hexane soln. of n-BuLi to 2-bromo-4-picoline in THF at -78°C, after 0.5 h Bu3SnCl added, stirred at -78°C (monitored by TLC), warmed to room temp., addn. of a satd. aq. soln. of NH4Cl; org. phase sepd., aq. phase extracted with Et2O, combined org. layers washed with brine, dried over Na2SO4, evapn. under vac., chromy. (Al2O3, EtOAc/hexane (1/20));
参考文献
Nierengarten, Helene; Rojo, Javier; Leize, Emmanuelle; Lehn, Jean-Marie; Van Dorsselaer, Alain
European Journal of Inorganic Chemistry, 2002 , # 3 p. 573 - 579
