4-甲氧基-1-苯并噻吩-2-羧酸甲酯合成路线 (共 3 条)
参考文献
Alanine, Alexander; Flohr, Alexander
Patent: US2003/149030 A1, 2003 ;
反应条件
1.1: LDA / tetrahydrofuran / -78 °C 1.2: tetrahydrofuran 2.1: K2CO3 / dimethylformamide View Scheme
参考文献
Bridges, Alexander J.; Lee, Arthur; Maduakor, Emmanuel C.; Eric Schwartz
Tetrahedron Letters, 1992 , vol. 33, # 49 p. 7499 - 7502
反应条件
sodium hydride 1.) DMSO, 20 deg C, 2.) DMSO, 2-5 min; Yield given. Multistep reaction;
参考文献
Lee, Sunkyung; Lee, Hyunsuk; Kyu, Yang Yi; Byung, Ho Lee; Yoo, Sung-Eun; Lee, Kyunghee; Nam, Sook Cho
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 12 p. 2998 - 3001