1: lithium chloride; lithium diisopropyl amide / tetrahydrofuran / -78 - 20 °C / |Inert atmosphere 2: ammonium cerium (IV) nitrate / water; acetonitrile / 1 h / 0 °C / |Inert atmosphere View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1.1: triethylamine / dichloromethane / 0.17 h / |Inert atmosphere; |Molecular sieve<br />1.2: 18 h / 20 &deg;C / |Inert atmosphere; |Molecular sieve<br />1.3: 18 h / 20 &deg;C / |Inert atmosphere<br />2.1: triethylamine / ethylene glycol dimethyl ether / 0.17 h / |Inert atmosphere<br />2.2: 20 h / |Inert atmosphere; |Reflux<br />3.1: lithium hydroxide hydrate / water; tetrahydrofuran / 20 h / 45 &deg;C / |Inert atmosphere<br /> <br /> &nbsp;