1: 94 percent / toluene / 20 h / Heating 2: 80 percent / CH2Cl2 / 168 h / Heating 3: 76 percent / aq. HCl / ethanol / 5 h / 20 °C 4: H2O / 2 h / 20 °C 5: 9.3 mg / Et3SiH; CF3CO2H / CH2Cl2 / 0.5 h / Heating 6: 54 percent / H2 / Pd/C / aq. ethanol / 1.5 h 7: DEAD; PPh3 / toluene / 0.08 h / 20 °C View Scheme

1: H2O / 2 h / 20 °C 2: 9.3 mg / Et3SiH; CF3CO2H / CH2Cl2 / 0.5 h / Heating 3: 54 percent / H2 / Pd/C / aq. ethanol / 1.5 h 4: DEAD; PPh3 / toluene / 0.08 h / 20 °C View Scheme

1: 54 percent / H2 / Pd/C / aq. ethanol / 1.5 h 2: DEAD; PPh3 / toluene / 0.08 h / 20 °C View Scheme

1: 9.3 mg / Et3SiH; CF3CO2H / CH2Cl2 / 0.5 h / Heating 2: 54 percent / H2 / Pd/C / aq. ethanol / 1.5 h 3: DEAD; PPh3 / toluene / 0.08 h / 20 °C View Scheme

triphenylphosphine; diethylazodicarboxylate in toluene T=20°C; Mitsunobu reaction; 0.0833333 h;

sodium hydroxide in methanol T=20°C; 0.25 h;