4-氯-5-甲氧基-2-甲基-2,3-二氢哒嗪-3-酮合成路线 （共 16 条）
反应条件
potassium carbonate
20 h; Heating;
参考文献
Chung, Hyun-A.; Kim, Jeum-Jong; Kim, Ho-Kyun; Kweon, Deok-Heon; Cho, Su-Dong; Lee, Sang-Gyeong; Yoon, Yong-Jin
Journal of Heterocyclic Chemistry, 2005 , vol. 42, # 4 p. 639 - 646
反应条件
18-crown-6 ether; potassium carbonate in 1,4-dioxane
20 h; Reflux;
参考文献
Li, Qin; Lin, Guichun; Liu, Li; Yang, Zhenjun; Zhang, Li-He
Molecules, 2009 , vol. 14, # 2 p. 777 - 784
反应条件
in N,N-dimethyl-formamide
Heating;
参考文献
Sotelo, Eddy; Ravina, Enrique
Synthetic Communications, 2002 , vol. 32, # 11 p. 1675 - 1680
反应条件
potassium carbonate
8 h; Heating;
参考文献
Cho, Su-Dong; Choi, Woo-Yong; Yoon, Yong-Jin
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 6 p. 1579 - 1582
反应条件
morpholine
T=100°C; 2 h;
参考文献
Nagashima, Hiromu; Oda, Hirohisa; Hayakawa, Takahisa; Kaji, Kenji
Heterocycles, 1987 , vol. 26, # 1 p. 1 - 4
反应条件
1: KOH / H2O / Heating
2: Et3N / CH2Cl2 / 0.5 h / -5 °C
3: 83 percent / Pd2Cl2(PPh3)2; CuI; n-Bu4NI / Et3N / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
R'kyek, Omar; Maes, Bert U.W; Jonckers, Tim H.M; Lemiere, Guy L.F; Dommisse, Roger A
Tetrahedron, 2001 , vol. 57, # 50 p. 10009 - 10016
