二(三甲基甲硅烷基)乙炔合成路线 （共 218 条）
反应条件
triethylamine
byproducts: H2; TEA was added in 9 portions at -196°C, after each addition stirring 2 h at 0°C, 2 h at room temperature; then 4 days at room temperature; fractionated through traps, sepn. with fractionating volatiles;
参考文献
Hosmane, Narayan S.; Sirmokadam, Narayan N.; Mollenhauser, Mark N.
Journal of Organometallic Chemistry, 1985 , vol. 279, p. 359 - 372
反应条件
pyrrolidine; copper(l) iodide; 4,4'-dichlorobenzophenone oxime derived palladacycle in 1-methyl-pyrrolidin-2-one
T=110°C; sila-Sonogashira reaction; 8 h;
参考文献
Alonso, Diego A.; Botella, Luis; Najera; Pacheco, Ma. Carmen
Synthesis, 2004 , # 10 p. 1713 - 1718
反应条件
copper(l) iodide; bis(benzonitrile)palladium(II) dichloride; (benzyl)-tri-(butyl)-ammonium chloride; sodium hydroxide; [(t-Bu)3PH]BF4 in water; toluene
T=40°C; Sonogashira coupling; 22 h; Inert atmosphere;
参考文献
Bellina, Fabio; Lessi, Marco
Synlett, 2012 , vol. 23, # 5 p. 773 - 777
反应条件
AlCl3, aluminium chloride in pentane
T=0°C; Friedel Crafts acylation;
参考文献
Klein, Oliver; Hopf, Henning; Grunenberg, Jorg
European Journal of Organic Chemistry, 2009 , # 13 p. 2141 - 2148
反应条件
Acylation; Friedel-Crafts reaction;
参考文献
Lee, Phil Ho; Park, Jaekeun; Lee, Kooyeon; Kim, Hyoung-Chun
Tetrahedron Letters, 1999 , vol. 40, # 39 p. 7109 - 7112
反应条件
1: para-iodobenzonitrile; bis(trimethylsilyl)-acetylene With tetrakis(triphenylphosphine) palladium(0); copper(l) chloride in N,N-dimethyl-formamide
T=80°C; sila-Sonogashira-Hagihara cross-coupling; 0.5 h; Inert atmosphere;
2: para-iodoanisole With tetrakis(triphenylphosphine) palladium(0); copper(l) chloride in N,N-dimethyl-formamide
T=80°C; sila-Sonogashira-Hagihara cross-coupling; 9 h; Inert atmosphere;
参考文献
Nishihara, Yasushi; Inoue, Eiji; Noyori, Shintaro; Ogawa, Daisuke; Okada, Yoshiaki; Iwasaki, Masayuki; Takagi, Kentaro
Tetrahedron, 2012 , vol. 68, # 24 p. 4869 - 4881
反应条件
1: With aluminium trichloride in dichloromethane
T=0 - 20°C; 4 h;
2: With tetrabutyl-ammonium chloride; NAF in diethyl ether; water
参考文献
Heiss, Christian; Laivenieks, Maris; Zeikus; Phillips, Robert S.
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 7 p. 1659 - 1666
参考文献
Seyferth, Dietmar; Annarelli, Dennis C.; Vick, Steven C.
Journal of Organometallic Chemistry, 1984 , vol. 272, # 2 p. 123 - 140
反应条件
(i) AlCl3, (ii) aq. MeOH; Multistep reaction;
参考文献
Deleris,G. et al.
Tetrahedron Letters, 1976 , p. 2449 - 2450
反应条件
(i) nBuLi, Et2O, (ii) /BRN= 1209714/; Multistep reaction;
参考文献
Priester,W.; West,R.
Journal of the American Chemical Society, 1976 , vol. 98, p. 8421 - 8425
