1: 4-acetylamino-1,2-dihydro-2-pyrimidone With chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane in 1,2-dichloro-ethane 3 h; Heating / reflux; 2: 3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-D-ribofuranosyl mesylate With trimethylsilyl trifluoromethanesulfonate in 1,2-dichloro-ethane T=20 - 75°C; 14 - 16 h; Heating / reflux; 3: With hydrogenchloride in water; 1,2-dichloro-ethane

1: With benzenesulfonamide in acetonitrile 1 h; Heating; 2: With trimethylsilyl trifluoromethanesulfonate T=20°C; 5 h; 3: With ammonium hydroxide in tetrahydrofuran; methanol T=50°C; 6 h; Further stages.;

ammonium sulfate 3 h; Heating;

trimethylsilyl trifluoromethanesulfonate; triethylamine in toluene T=20°C; 1 h;

in dichloromethane T=65°C;

暂无反应条件数据

ammonium sulfate T=125°C;

P2O5; chloro-trimethyl-silane 1.) 100 deg C, 24 h; 2.) reflux, 4 h; Yield given. Multistep reaction;