5,6,7,8-四氢-8-羟基喹啉合成路线 （共 16 条）
反应条件
potassium carbonate in methanol T=20°C;
参考文献
US6750348 B1, ;
Page column 15 ;
US 6750348 B1
反应条件
sodium tetrahydroborate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran T=25°C; 0.5 h; Inert atmosphere;
参考文献
Chelucci, Giorgio
Tetrahedron Letters, 2010 , vol. 51, # 12 p. 1562 - 1565
反应条件
hydrogen; trifluoroacetic acid; platinum(IV) oxide
参考文献
Kaiser, Stefan; Smidt, Sebastian P.; Pfaltz, Andreas
Angewandte Chemie - International Edition, 2006 , vol. 45, # 31 p. 5194 - 5197
反应条件
1: With trifluoroacetic anhydride in dichloromethane T=0 - 20°C; 16 h; 2: With lithium hydroxide in dichloromethane; water T=20°C; 16 h;
参考文献
Organic Letters, , vol. 8, # 9 p. 1879 - 1882
反应条件
4-(N,N-dimethlyamino)pyridine; methanesulfonyl chloride in dichloromethane T=20°C; 3 h;
参考文献
Synthesis, , # 5 p. 625 - 630
反应条件
hydrogen; platinum(IV) oxide in trifluoroacetic acid
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1933 - 1939
反应条件
1.1: mCPBA / CH2Cl2 / 16 h / 20 °C 2.1: trifluoroacetic anhydride / CH2Cl2 / 16 h / 0 - 20 °C 2.2: lithium hydroxide / CH2Cl2; H2O / 16 h / 20 °C View Scheme
参考文献
Organic Letters, , vol. 8, # 9 p. 1879 - 1882
反应条件
1: 48percent HBr / 24 h 2: 38 percent / hydrogen / platinum oxide / trifluoroacetic acid View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1933 - 1939
反应条件
2: 48percent HBr / 24 h 3: 38 percent / hydrogen / platinum oxide / trifluoroacetic acid View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1933 - 1939
反应条件
1: 88 percent / K2CO3 / methanol / 2 h / 20 °C 2: 66 percent / DMAP; MsCl / CH2Cl2 / 3 h / 20 °C View Scheme
参考文献
Synthesis, , # 5 p. 625 - 630
