(3S)-4-羟基-3-[[(苯基甲氧基)羰基]氨基]-丁酸-1,1-二甲基乙酯合成路线 (共 4 条)
反应条件
4-methyl-morpholine; sodium tetrahydroborate; isobutyl chloroformate in tetrahydrofuran T=-78°C; Reduction; 0.333333 h;
参考文献
Mindt, Thomas; Michel, Urs; Dick
Helvetica Chimica Acta, 1999 , vol. 82, # 11 p. 1960 - 1968
反应条件
(n-Hex)CuCNLi2 in tetrahydrofuran T=-40°C;
参考文献
Buron, Frederic; Turck, Alain; Ple, Nelly; Bischoff, Laurent; Marsais, Francis
Tetrahedron Letters, 2007 , vol. 48, # 25 p. 4327 - 4330
反应条件
sodium tetrahydroborate in tetrahydrofuran T=0°C; Reduction;
参考文献
Jadhav, Sandip V.; Misra, Rajkumar; Singh, Sumeet K.; Gopi, Hosahudya N.
Chemistry - A European Journal, 2013 , vol. 19, # 48 p. 16256 - 16262
反应条件
sodium tetrahydroborate in ethylene glycol dimethyl ether; water 1 h; cooling;
参考文献
Buron, Frederic; Turck, Alain; Ple, Nelly; Bischoff, Laurent; Marsais, Francis
Tetrahedron Letters, 2007 , vol. 48, # 25 p. 4327 - 4330