二(2-甲基-2-丙基)2,2'-[(2-溴乙基)亚氨基]二乙酸酯合成路线 （共 4 条）
反应条件
thionyl bromide; N,N-dimethyl-formamide in hexane T=20°C;
参考文献
Dakanali, Marianna; Tsikalas, George K.; Krautscheid, Harald; Katerinopoulos, Haralambos E.
Tetrahedron Letters, 2008 , vol. 49, # 10 p. 1648 - 1651
反应条件
N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=20°C;
参考文献
Azuma, Yusuke; Imanishi, Miki; Yoshimura, Tomoyuki; Kawabata, Takeo; Futaki, Shiroh
Angewandte Chemie, International Edition, 2009 , vol. 48, # 37 p. 6853 - 6856
Angewandte Chemie, 2009 , vol. 121, # 37 p. 6985 - 6988
反应条件
1: With potassium hydrogencarbonate in N,N-dimethyl-formamide T=20°C; 20 h; 2: With N-bromosuccinmide; triphenylphosphine in dichloromethane 1 h;
参考文献
Micklitsch, Christopher M.; Yu, Qian; Schneider, Joel P.
Tetrahedron Letters, 2006 , vol. 47, # 35 p. 6277 - 6280
反应条件
1: KHCO3 / dimethylformamide / 24.5 h / 0 - 20 °C 2: 1.7 g / triphenylphosphine; N-bromosuccinimide / CH2Cl2 / 2 h / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 23 p. 7666 - 7670
