Boc-γ-L-二高亮氨酸合成路线 （共 16 条）
反应条件
1: 95 percent / Et3N / dioxane; H2O / 4 h / Ambient temperature 2: Et3N / tetrahydrofuran / 0.5 h / -10 °C 3: NaBH4 / H2O; tetrahydrofuran / 4 h / Ambient temperature 4: pyridine / -5 °C 5: NaI / acetone / 4 h / Heating 6: tetrahydrofuran / 0.17 h / -50 °C 7: 2N NaOH / dioxane; H2O / Ambient temperature View Scheme
参考文献
Synthesis, , # 11 p. 1104 - 1108
反应条件
1: 95 percent / Et3N / dioxane; H2O / 4 h / Ambient temperature 2: Et3N / tetrahydrofuran / 0.5 h / -10 °C 3: NaBH4 / H2O; tetrahydrofuran / 4 h / Ambient temperature 4: pyridine / -5 °C 5: NaI / acetone / 4 h / Heating 6: tetrahydrofuran / 0.17 h / -50 °C 7: 2N NaOH / dioxane; H2O / Ambient temperature View Scheme
参考文献
Synthesis, , # 11 p. 1104 - 1108
反应条件
1: Et3N / tetrahydrofuran / 0.5 h / -10 °C 2: NaBH4 / H2O; tetrahydrofuran / 4 h / Ambient temperature 3: pyridine / -5 °C 4: NaI / acetone / 4 h / Heating 5: tetrahydrofuran / 0.17 h / -50 °C 6: 2N NaOH / dioxane; H2O / Ambient temperature View Scheme
参考文献
Synthesis, , # 11 p. 1104 - 1108
反应条件
1: pyridine / -5 °C 2: NaI / acetone / 4 h / Heating 3: tetrahydrofuran / 0.17 h / -50 °C 4: 2N NaOH / dioxane; H2O / Ambient temperature View Scheme
参考文献
Synthesis, , # 11 p. 1104 - 1108
反应条件
1: tetrahydrofuran / 0.17 h / -50 °C 2: 2N NaOH / dioxane; H2O / Ambient temperature View Scheme
参考文献
Synthesis, , # 11 p. 1104 - 1108
反应条件
1: NaI / acetone / 4 h / Heating 2: tetrahydrofuran / 0.17 h / -50 °C 3: 2N NaOH / dioxane; H2O / Ambient temperature View Scheme
参考文献
Synthesis, , # 11 p. 1104 - 1108
