1: 70 percent / H2; acetic acid / platinum(IV) oxide / 3800 Torr 2: 98 percent / diisobutylaluminum hydride / toluene; hexane / 0.5 h / -78 °C 3: 93 percent / benzene / 3 h / 60 °C 4: 99 percent / diisobutylaluminum hydride / toluene; hexane / 0.25 h / -68 - 0 °C 5: 96 percent / triphenylphosphine; diisopropyl azodicarboxylate / tetrahydrofuran; toluene / 3 h / 0 °C 6: 87 percent / (NH4)6Mo7O24*4H2O; H2O2 / ethanol / 2 h / 20 °C 7: HCl / ethyl acetate / 1.5 h / 20 °C 8: 84 mg / N-ethylmorpholine; HBTU / acetonitrile / 18 h / 20 °C 9: 68 percent / LHMDS / tetrahydrofuran; hexane / 3 h / -78 - 20 °C 10: 85 percent / HCl / methanol / 10 h / -20 °C 11: 98 percent / triethylamine; DMAP / CH2Cl2 / 1.5 h / 0 °C 12: 97 percent / TBAF / tetrahydrofuran / 3 h / 0 °C 13: 36 percent / Amberlyst 15 / tetrahydrofuran; H2O / 20 h / 20 °C View Scheme

1: Grubb's 2nd generation catalyst / dichloromethane / 5 h / |Inert atmosphere; |Reflux 2: pyridinium p-toluenesulfonate / tetrahydrofuran; water / 72 h / 0 °C / |Inert atmosphere View Scheme

1: 68 percent / LHMDS / tetrahydrofuran; hexane / 3 h / -78 - 20 °C 2: 85 percent / HCl / methanol / 10 h / -20 °C 3: 98 percent / triethylamine; DMAP / CH2Cl2 / 1.5 h / 0 °C 4: 97 percent / TBAF / tetrahydrofuran / 3 h / 0 °C 5: 36 percent / Amberlyst 15 / tetrahydrofuran; H2O / 20 h / 20 °C View Scheme

1: 70 percent / dimethylformamide / 48 h / 70 °C 2: 91 percent / diisobutylaluminum hydride / tetrahydrofuran; hexane / 2 h / -40 °C 3: 91 percent / molecular sieves 4 Angstroem; NMO; TPAP / CH2Cl2 / 3 h / 20 °C 4: 68 percent / LHMDS / tetrahydrofuran; hexane / 3 h / -78 - 20 °C 5: 85 percent / HCl / methanol / 10 h / -20 °C 6: 98 percent / triethylamine; DMAP / CH2Cl2 / 1.5 h / 0 °C 7: 97 percent / TBAF / tetrahydrofuran / 3 h / 0 °C 8: 36 percent / Amberlyst 15 / tetrahydrofuran; H2O / 20 h / 20 °C View Scheme

1: 91 percent / molecular sieves 4 Angstroem; NMO; TPAP / CH2Cl2 / 3 h / 20 °C 2: 68 percent / LHMDS / tetrahydrofuran; hexane / 3 h / -78 - 20 °C 3: 85 percent / HCl / methanol / 10 h / -20 °C 4: 98 percent / triethylamine; DMAP / CH2Cl2 / 1.5 h / 0 °C 5: 97 percent / TBAF / tetrahydrofuran / 3 h / 0 °C 6: 36 percent / Amberlyst 15 / tetrahydrofuran; H2O / 20 h / 20 °C View Scheme

1: 91 percent / diisobutylaluminum hydride / tetrahydrofuran; hexane / 2 h / -40 °C 2: 91 percent / molecular sieves 4 Angstroem; NMO; TPAP / CH2Cl2 / 3 h / 20 °C 3: 68 percent / LHMDS / tetrahydrofuran; hexane / 3 h / -78 - 20 °C 4: 85 percent / HCl / methanol / 10 h / -20 °C 5: 98 percent / triethylamine; DMAP / CH2Cl2 / 1.5 h / 0 °C 6: 97 percent / TBAF / tetrahydrofuran / 3 h / 0 °C 7: 36 percent / Amberlyst 15 / tetrahydrofuran; H2O / 20 h / 20 °C View Scheme

1: 84 mg / N-ethylmorpholine; HBTU / acetonitrile / 18 h / 20 °C 2: 68 percent / LHMDS / tetrahydrofuran; hexane / 3 h / -78 - 20 °C 3: 85 percent / HCl / methanol / 10 h / -20 °C 4: 98 percent / triethylamine; DMAP / CH2Cl2 / 1.5 h / 0 °C 5: 97 percent / TBAF / tetrahydrofuran / 3 h / 0 °C 6: 36 percent / Amberlyst 15 / tetrahydrofuran; H2O / 20 h / 20 °C View Scheme

1: 87 percent / (NH4)6Mo7O24*4H2O; H2O2 / ethanol / 2 h / 20 °C 2: HCl / ethyl acetate / 1.5 h / 20 °C 3: 84 mg / N-ethylmorpholine; HBTU / acetonitrile / 18 h / 20 °C 4: 68 percent / LHMDS / tetrahydrofuran; hexane / 3 h / -78 - 20 °C 5: 85 percent / HCl / methanol / 10 h / -20 °C 6: 98 percent / triethylamine; DMAP / CH2Cl2 / 1.5 h / 0 °C 7: 97 percent / TBAF / tetrahydrofuran / 3 h / 0 °C 8: 36 percent / Amberlyst 15 / tetrahydrofuran; H2O / 20 h / 20 °C View Scheme

1: HCl / ethyl acetate / 1.5 h / 20 °C 2: 84 mg / N-ethylmorpholine; HBTU / acetonitrile / 18 h / 20 °C 3: 68 percent / LHMDS / tetrahydrofuran; hexane / 3 h / -78 - 20 °C 4: 85 percent / HCl / methanol / 10 h / -20 °C 5: 98 percent / triethylamine; DMAP / CH2Cl2 / 1.5 h / 0 °C 6: 97 percent / TBAF / tetrahydrofuran / 3 h / 0 °C 7: 36 percent / Amberlyst 15 / tetrahydrofuran; H2O / 20 h / 20 °C View Scheme

1: 68 percent / LHMDS / tetrahydrofuran; hexane / 3 h / -78 - 20 °C 2: 85 percent / HCl / methanol / 10 h / -20 °C 3: 98 percent / triethylamine; DMAP / CH2Cl2 / 1.5 h / 0 °C 4: 97 percent / TBAF / tetrahydrofuran / 3 h / 0 °C 5: 36 percent / Amberlyst 15 / tetrahydrofuran; H2O / 20 h / 20 °C View Scheme