1: 1.) Zn(Ag), Cu(I)Br, Et2AlCl / 1.) THF, hexane, 1 h, 2.) THF, RT, 1.5 h 2: 96 percent / CH2Cl2 / 18 h / Ambient temperature 3: oxalyl chloride, DMF / CH2Cl2 / 1.) 0 deg C, 10 min, 2.) RT, 4 h 4: NaBH4 / dimethylformamide 5: ammonium formate / Pd/C (10percent) / methanol / 1.) RT, 10 min, 2.) 60-70 deg C, 21 h 6: 2 N aq. HCl / methanol View Scheme