Fmoc-L-烯丙基甘氨酸合成路线 （共 14 条）
反应条件
1: With sodium hydrogencarbonate in water; acetone T=20°C; 20 h; 2: With hydrogenchloride in water; acetone pH=2;
参考文献
Robinson, Andrea; Elaridi, Jomana
Patent: US2007/197429 A1, 2007 ;
Location in patent: Page/Page column 74-75 ;
反应条件
sodium hydrogencarbonate in 1,4-dioxane T=0 - 20°C; 4.75 h;
参考文献
Besada, Pedro; Mamedova, Liaman; Thomas, Craig J.; Costanzi, Stefano; Jacobson, Kenneth A.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 10 p. 2016 - 2025
反应条件
water; chlortris(triphenylphosphine)rhodium in ethanol 2 h;
参考文献
Oppolzer, Wolfgang; Lienard, Philippe
Helvetica Chimica Acta, 1992 , vol. 75, # 8 p. 2572 - 2582
反应条件
sodium hydrogencarbonate in 1,4-dioxane; water Inert atmosphereReflux;
参考文献
European Journal of Medicinal Chemistry, , vol. 69, p. 232 - 243
反应条件
sodium hydrogencarbonate in water; acetone T=20°C;
参考文献
Organic Letters, , vol. 6, # 19 p. 3285 - 3288
反应条件
1: Na2CO3 / tetrahydrofuran / 3 h / Ambient temperature 2: 75 percent / Ti(OEt)4 / 1 h / 130 °C 3: 97 percent / H2O / <RhCl(PPh3)> / ethanol / 2 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 75, # 8 p. 2572 - 2582
反应条件
1: Na2CO3 / tetrahydrofuran / 3 h / Ambient temperature 2: 75 percent / Ti(OEt)4 / 1 h / 130 °C 3: 97 percent / H2O / <RhCl(PPh3)> / ethanol / 2 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 75, # 8 p. 2572 - 2582
反应条件
1: 1 N aq. HCl / tetrahydrofuran / 24 h / Ambient temperature 2: Na2CO3 / tetrahydrofuran / 3 h / Ambient temperature 3: 75 percent / Ti(OEt)4 / 1 h / 130 °C 4: 97 percent / H2O / <RhCl(PPh3)> / ethanol / 2 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 75, # 8 p. 2572 - 2582
反应条件
[Rh(COD)(1,4-bis(diphenylphosphino)butane)]BF4; hydrogen in methanol-d4 P=1500.15 Torr; 0.00277778 h;
参考文献
Chemical Communications, , vol. 49, # 71 p. 7840 - 7841
反应条件
1: 94 percent / TFA; Et3SiH / CH2Cl2 / 15 h 2: 70 percent / NaOH / H2O; acetone / 18 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 70, # 10 p. 3838 - 3844
