(R)-1-(甲氧基(甲基)氨基)-1-氧代-2-丙基氨基甲酸叔丁酯合成路线 （共 16 条）
反应条件
1: LiAlH4 / tetrahydrofuran 2: CH2Cl2 3: LiOH / methanol; H2O View Scheme
参考文献
Hagihara, Masahiko; Anthony, Neville J.; Stout, Thomas J.; Clardy, Jon; Schreiber, Stuart L.
Journal of the American Chemical Society, 1992 , vol. 114, # l6 p. 6568 - 6570
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=-20°C;
参考文献
Conroy, Trent; Guo, Jin T.; Linington, Roger G.; Hunt, Nicholas H.; Payne, Richard J.
Chemistry - A European Journal, 2011 , vol. 17, # 48 p. 13544 - 13552
反应条件
1: t-butyl N-{(1S)-2-[methoxy(methyl)amino]-1-methyl-2-oxoethyl}carbamate With diisobutylaluminium hydride in n-heptane; dichloromethane T=-78°C; 2: (1-Diazo-2-oxo-propyl)-phosphonic acid dimethyl ester With potassium carbonate in methanol; n-heptane; dichloromethane T=20°C; Further stages.;
参考文献
Tetrahedron Letters, , vol. 45, # 29 p. 5597 - 5599
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=0°C; 1 h;
参考文献
Boger, Dale L.; Menezes, Royce F.
Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4331 - 4333
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Boger, Dale L.; Colletti, Steven L.; Honda, Takeshi; Menezes, Royce F.
Journal of the American Chemical Society, 1994 , vol. 116, # 13 p. 5607 - 5618
反应条件
isopropylmagnesium chloride in tetrahydrofuran
T=-15 - 20°C;
参考文献
Liu, Jinchu; Ikemoto, Norihiro; Petrillo, Daniel; Armstrong III, Joseph D.
Tetrahedron Letters, 2002 , vol. 43, # 46 p. 8223 - 8226
反应条件
in tetrahydrofuran
4 h;
参考文献
Zhou, Zheng Hong; Tang, Yi Long; Li, Kang Ying; Liu, Bing; Tang, Chu Chi
Heteroatom Chemistry, 2003 , vol. 14, # 7 p. 603 - 606
