2,6-二甲氧基苯甲酸合成路线 （共 118 条）
反应条件
copper(I) oxide; palladium diacetate; dimethyl sulfoxide; silver carbonate in toluene T=110°C; 2 h; chemoselective reaction;
参考文献
Wang, Jiantao; Cui, Zili; Zhang, Yuexia; Li, Huajie; Wu, Long-Min; Liu, Zhongquan
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 3 p. 663 - 666
反应条件
DCAD; triphenylphosphine in dichloromethane T=20°C; Mitsunobu reaction; 0.55 h;
参考文献
Lipshutz, Bruce H.; Chung, David W.; Rich, Brian; Corral, Ricardo
Organic Letters, 2006 , vol. 8, # 22 p. 5069 - 5072
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl acetamide T=135°C; 2 h;
参考文献
Shieh, Wen-Chung; Lozanov, Mario; Loo, Mauricio; Repic, Oljan; Blacklock, Thomas J.
Tetrahedron Letters, 2003 , vol. 44, # 24 p. 4563 - 4565
反应条件
1: BH3 / tetrahydrofuran / 2 h / Heating 2: 74 percent / H2O / 0.17 h / Irradiation View Scheme
参考文献
Wan, Peter; Chak, Becky
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1986 , p. 1751 - 1756
反应条件
thionyl chloride in chloroform T=50°C; 0.5 h;
参考文献
Florvall, Lennart; Oegren, Sven-Ove
Journal of Medicinal Chemistry, 1982 , vol. 25, # 11 p. 1280 - 1286
反应条件
trifluoroacetic acid; palladium (II) trifluoroacetate in dimethyl sulfoxide; N,N-dimethyl-formamide T=70°C; 24 h;
参考文献
Organic Letters, , vol. 9, # 13 p. 2441 - 2444
反应条件
palladium diacetate; silver carbonate; di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine in dimethylsulfoxide-d6 T=200°C; 0.0833333 h; MicrowaveMolecular sieve;
参考文献
Chemical Communications, , # 47 p. 6312 - 6314
反应条件
palladium diacetate; silver carbonate; di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine in dimethyl sulfoxide; N,N-dimethyl-formamide T=200°C; MicrowaveMolecular sieve;
参考文献
Chemical Communications, , # 47 p. 6312 - 6314
反应条件
palladium diacetate; silver carbonate; di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine in dimethylsulfoxide-d6 T=200°C; 0.0833333 h; MicrowaveMolecular sieve;
参考文献
Chemical Communications, , # 47 p. 6312 - 6314
反应条件
palladium diacetate; silver carbonate; di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine in dimethylsulfoxide-d6 T=200°C; 0.0833333 h; MicrowaveMolecular sieve;
参考文献
Chemical Communications, , # 47 p. 6312 - 6314
