4-(2-甲氧基苯基)-N-2-吡啶基-1-哌嗪乙酰胺合成路线 (共 7 条)
反应条件
potassium carbonate in N,N-dimethyl-formamide Substitution; 18 h;
参考文献
Pike, Victor W.; McCarron, Julie A.; Hume, Susan P.; Ashworth, Sharon; Opacka-Juffry, Jolanta; et al.
Medicinal Chemistry Research, 1995 , vol. 5, # 2/3 p. 208 - 227
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
O'Connor, Naphtali A.; Paisner, David A.; Huryn, Donna; Shea, Kenneth J.
Journal of the American Chemical Society, 2007 , vol. 129, # 6 p. 1680 - 1689
反应条件
1: 56 percent / acetonitrile 2: 83 percent / K2CO3 / dimethylformamide View Scheme
参考文献
Zhuang; Kung
Journal of Medicinal Chemistry, 1994 , vol. 37, # 10 p. 1406 - 1407
反应条件
1: LAH / tetrahydrofuran 2: Et3N / CH2Cl2 View Scheme
参考文献
Zhuang; Kung
Journal of Medicinal Chemistry, 1994 , vol. 37, # 10 p. 1406 - 1407
反应条件
1: 90 percent / LiAlH4 / tetrahydrofuran 2: 75 percent / Et3N / acetonitrile View Scheme
参考文献
Zhuang; Kung
Journal of Medicinal Chemistry, 1994 , vol. 37, # 10 p. 1406 - 1407
反应条件
1: 90 percent / LiAlH4 / tetrahydrofuran 2: 86 percent / Et3N / acetonitrile View Scheme
参考文献
Wilson, Alan A.; DaSilva, Jean N.; Inaba, T.; Fischer, N.; Houle, S.
Journal of Labelled Compounds and Radiopharmaceuticals, 1997 , vol. 40, p. 531 - 533
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=80°C; 0.0833333 h; Microwave irradiation;
参考文献
US2007/36715 A1, ;
Page/Page column 6 ;