pyridine-2,6-dicarboxylate N-oxide; ammonium cerium(IV) nitrate in water; acetonitrile 1.) 0 deg C, 30 min, 2.) 20 deg C, 30 min;

1: base 2: aq. ceric ammonium nitrate / acetonitrile / 0.75 h View Scheme

1: 76 percent / Fe, conc. HCl / ethanol; acetic acid; H2O / 0.25 h / Heating 2: 75 percent / KOH / ethanol / 18 h / Heating 3: 85 percent / ceric ammonium nitrate, pyridine-2,6-dicarboxylic acid N-oxide / acetonitrile; H2O / 1.) 0 deg C, 30 min, 2.) 20 deg C, 30 min View Scheme

1: base 2: aq. ceric ammonium nitrate / acetonitrile / 0.75 h View Scheme