1: tBuLi / diethyl ether / 1.5 h / -78 °C 2: 2) 1 N HCl / 1) a) -78 deg C, 5 min., b) 0 deg C, 2) 0 deg C, 10 -30 min. View Scheme

1: tBuLi / diethyl ether / 1.5 h / -78 °C 2: 2) 1 N HCl / 1) a) -78 deg C, 5 min., b) 0 deg C, 2) 0 deg C, 10 -30 min. View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3556712', constants.ctx, '0')">potassium <i>tert</i>-butylate</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '4154566', constants.ctx, '0')">sodium carbonate</a> <br />&nbsp;1) THF, -70 deg C, 90 min.;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;