(R)-1-Boc-3-氨基吡咯烷合成路线 （共 13 条）
反应条件
sodium cyanoborohydride; magnesium sulfate; acetic acid in methanol T=20°C; 24 h;
参考文献
KBP Biosciences Co., Ltd.; HUANG, Zhenhua; WANG, Jinyuan; ZHANG, Dedong
Patent: EP2607363 A1, 2013 ;
Location in patent: Paragraph 0130 ;
反应条件
1: With sodium cyanoborohydride; acetic acid in methanol 10 h; Reflux; 2: With water in methanol
参考文献
WO2012/22265 A1, ;
Page/Page column 33; 34 ;
WO 2012/022265 A1
反应条件
in chloroform
T=23°C; 1 h;
参考文献
Miller, Shawn M.; Samame, Renzo A.; Rychnovsky, Scott D.
Journal of the American Chemical Society, 2012 , vol. 134, # 50 p. 20318 - 20321
