2-(4-氯-2-硝基苯基)乙酸甲酯合成路线 （共 4 条）
反应条件
water in 1-methyl-pyrrolidin-2-one 3.5 h; Heating / reflux;
参考文献
PFIZER INC.
Patent: WO2004/56806 A1, 2004 ;
Location in patent: Page 36 ;
WO 2004/056806 A1
反应条件
lithium chloride in water; dimethyl sulfoxide T=100°C; 3 h;
参考文献
Quallich; Morrissey
Synthesis, 1993 , # 1 p. 51 - 53
反应条件
1: 1) NaH / 1) DMSO, 100 deg C, 40 min, 2a) RT, 30 min, 2b) 100 deg C, 1 h 2: 69 percent / LiCl / dimethylsulfoxide; H2O / 3 h / 100 °C View Scheme
参考文献
Quallich; Morrissey
Synthesis, 1993 , # 1 p. 51 - 53
反应条件
iron in acetic acid T=100°C; 1 h;
参考文献
Synthesis, , # 1 p. 51 - 53
