(2S,4s)-1-(叔丁氧基羰基)-4-苯氧基-2-吡咯烷羧酸合成路线 （共 4 条）
反应条件
sodium hydroxide in tetrahydrofuran T=20°C; 12 h;
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1346982 A1, 2003 ;
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; 12 h;
参考文献
Zhang, Shu-peng; Fu, Xiang-kai; Fu, Shao-dong
Tetrahedron Letters, 2009 , vol. 50, # 11 p. 1173 - 1176
反应条件
1: 86 percent / diisopropyl azodicarboxylate; PPh3 / tetrahydrofuran / 12 h / 20 °C 2: 58 percent / aq. NaOH / tetrahydrofuran / 12 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 8 p. 2725 - 2746
反应条件
1: 86 percent / diisopropyl azodicarboxylate; PPh3 / tetrahydrofuran / 12 h / 20 °C 2: 58 percent / aq. NaOH / tetrahydrofuran / 12 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 8 p. 2725 - 2746
