6-(4-甲氧基苯基)-2-氧代-1,2-二氢-3-吡啶羧酸合成路线 （共 2 条）
反应条件
sodium hydroxide T=140°C; 12 h;
参考文献
Damewood Jr.; Edwards; Feeney; Gomes; Steelman; Tuthill; Williams; Warner; Woolson; Wolanin; Veale
Journal of Medicinal Chemistry, 1994 , vol. 37, # 20 p. 3303 - 3312
反应条件
1: 1.) MeONa, 2.) AcOH / 1.) THF, ether, 40 deg C, 3 h, 2.) water, 90 deg C, 18 h 2: 100 percent / 50percent aq.NaOH / 12 h / 140 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 20 p. 3303 - 3312
