toluene-4-sulfonic acid in toluene 0.0833333 h; Heating;

chloro-(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)(2-(N-acetylamino)-phenyl-C1,O)-palladium(II); sodium hydroxide in tetrahydrofuran; methanol T=20°C; Suzuki-Miyaura coupling; 18 h; Inert atmosphereSealed tube;

sodium azide; trifluoroacetic acid in chloroform T=0 - 20°C;

1: 1.) n-BuLi / 1.) Et2O, hexane, RT, 2.) Et2O, hexane, RT 2: 100 percent / p-toluenesulfonic acid / toluene / 0.08 h / Heating View Scheme

1: 1.) n-BuLi / 1.) Et2O, hexane, RT, 2.) Et2O, hexane, RT 2: 100 percent / p-toluenesulfonic acid / toluene / 0.08 h / Heating View Scheme