2-氨基-5-苯基-3-呋喃甲腈合成路线 (共 7 条)
反应条件
silica gel; diethylamine 0.25 h; neat (no solvent);
参考文献
Bakavoli, Mehdi; Rahimizadeh, Mohammad; Gordi, Zinat
Journal of Chemical Research, 2008 , # 10 p. 564 - 565
反应条件
hydrogenchloride in acetic acid 1 h; Heating;
参考文献
Abdelhamid, Abdou O.; Negm, Abdalla M.; Abbas, Ikhlass M.
Journal fuer Praktische Chemie (Leipzig), 1989 , vol. 331, # 1 p. 31 - 36
反应条件
hydrogenchloride in diethyl ether
参考文献
Foley, Louise H.
Tetrahedron Letters, 1994 , vol. 35, # 33 p. 5989 - 5992
反应条件
potassium hydroxide; water in methanol dehydrocyanation; 0.25 h;
参考文献
Nasakin; Sheverdov; Moiseeva; Ershov; Chernushkin; Tafeenko
Russian Journal of General Chemistry, 1999 , vol. 69, # 2 p. 291 - 300
反应条件
1: 95 percent / NaOH / ethanol; H2O 2: 70 percent / conc. hydrochloric acid / acetic acid / 1 h / Heating View Scheme
参考文献
Maeda, Yutaka; Nakano, Masato; Sato, Hideyuki; Miyazaki, Yasushi; Schweiker, Stephanie L.; Smith, Jeffery L.; Truesdale, Anne T.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 15 p. 3907 - 3911
反应条件
4-chloro pyridine hydrochloride in 1,4-dioxane T=70°C; 1.5 h;
参考文献
Feng, Xiao; Lancelot, Jean-Charles; Gillard, Alain-Claude; Landelle, Henriette; Rault, Sylvain
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 6 p. 1313 - 1316
反应条件
in dichloromethane T=210°C; 1.5 h;
参考文献
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
Patent: US2011/124665 A1, 2011 ;
Location in patent: Page/Page column 33 ;