反应条件
1: 1,4-diazabicyclo[2.2.2]octane / dimethylformamide / 230 °C 2: N,N-diethylaniline / Heating 3: KOH / methanol / Heating 4: K2CO3 / dimethylformamide / 20 °C View Scheme
参考文献
Albert, Jeffrey S.; Andisik, Donald; Barthlow, Herbert; Bernstein, Peter R.; Bialecki, Russell A.; Dedinas, Robert; Dembofsky, Bruce T.; Hill, Daniel; Kirkland, Karin; Koether, Gerard M.; Kosmider, Benedict J.; Ohnmacht, Cyrus; Palmer, William; Potts, William; Rumsey, William; Shen, Lihong; Shenvi, Ashok; Sherwood, Scott; Aharony, David; Warwick, Paul J.; Russell, Keith
Journal of Medicinal Chemistry, 2002 , vol. 45, # 18 p. 3972 - 3983