3-氧代-3-(2-甲苯基)丙酸甲酯合成路线 （共 5 条）
反应条件
1: With Tedicyp; sodium hydrogencarbonate; bis(η3-allyl-μ-chloropalladium(II)) in N,N-dimethyl-formamide T=150°C; Heck reaction; 20 h; 2: With hydrogenchloride in dichloromethane; water T=25°C;
参考文献
Battace, Ahmed; Feuerstein, Marie; Lemhadri, Mhamed; Zair, Touriya; Doucet, Henri; Santelli, Maurice
European Journal of Organic Chemistry, 2007 , # 19 p. 3122 - 3132
反应条件
sodium hydride in toluene T=20°C;
参考文献
BIOVITRUM AB (publ)
Patent: WO2009/90239 A1, 2009 ;
Location in patent: Page/Page column 16; 17 ;
反应条件
jones reagent in acetone T=5°C; Yield given;
参考文献
Saito, Masaichi; Kamei, Yumiko; Kuribara, Kanae; Yoshioka, Michikazu; Hasegawa, Tadashi
Journal of Organic Chemistry, 1998 , vol. 63, # 24 p. 9013 - 9018
反应条件
1: Zn / benzene / 5 h / Heating 2: Jones reagent / acetone / 5 °C View Scheme
参考文献
Saito, Masaichi; Kamei, Yumiko; Kuribara, Kanae; Yoshioka, Michikazu; Hasegawa, Tadashi
Journal of Organic Chemistry, 1998 , vol. 63, # 24 p. 9013 - 9018
反应条件
1: sodium hydrogencarbonate; bis(η3-allyl-μ-chloropalladium(II)); Tedicyp / N,N-dimethyl-formamide / 150 °C 2: sulfuric acid / tetrahydrofuran; water View Scheme
参考文献
Kohrt, Jeffrey T.; Conn, Ed; Maguire, Robert; Wright, Stephen W.; Singer, Robert
Tetrahedron Letters, 2013 , vol. 54, # 51 p. 7065 - 7068
