甲基2,3-二羟基-2-甲基丙酸酯合成路线 （共 5 条）
反应条件
1: thionyl chloride / CCl4 / Heating 2: sodium azide / dimethylformamide / 48 h / 50 °C View Scheme
参考文献
Avenoza, Alberto; Cativiela, Carlos; Corzana, Francisco; Peregrina, Jesus M.; Sucunza, David; Zurbano, Maria M.
Tetrahedron Asymmetry, 2001 , vol. 12, # 6 p. 949 - 957
反应条件
thionyl chloride in tetrachloromethane 4 h; Heating;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 6 p. 949 - 957
反应条件
1: Weinreb amide of 2-methyl-2-propeonic acid With K2OsO2(OH)4; methanesulfonamide; 1,4-bis(9-O-dihydroquinidine)phthalazine; potassium carbonate; potassium hexacyanoferrate(III) in water; tert-butyl alcohol
T=0 - 20°C; Sharpless asymmetric dihydroxylation;
2: With lithium hydroxide in methanol; water
T=20°C; 5 h;
3: methanol With acetyl chloride
Heating; Title compound not separated from byproducts;
参考文献
Smith, Nicole D.; Goodman, Murray
Organic Letters, 2003 , vol. 5, # 7 p. 1035 - 1037
参考文献
Rodriguez, Juan B.; Markey, Sanford P.; Ziffer, Herman
Tetrahedron: Asymmetry, 1993 , vol. 4, # 1 p. 101 - 108
参考文献
Yen; Uang
Tetrahedron Asymmetry, 1992 , vol. 3, # 6 p. 697 - 700
