2-丙烯基-2-丙炔氨基甲酸叔丁酯合成路线 （共 6 条）
反应条件
in tetrahydrofuran 120 h; Ambient temperature;
参考文献
Becker, Daniel P.; Flynn, Daniel L.
Tetrahedron, 1993 , vol. 49, # 23 p. 5047 - 5054
反应条件
KH in propargyl bromide; N,N-dimethyl-formamide
参考文献
Pfizer Inc
Patent: US6156752 A1, 2000 ;
US 6156752 A
反应条件
sodium hydride in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
Lemoine, Remy C.; Petersen, Ann C.; Setti, Lina; Baldinger, Thomas; Wanner, Jutta; Jekle, Andreas; Heilek, Gabrielle; deRosier, Andre; Ji, Changhua; Rotstein, David M.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 5 p. 1674 - 1676
反应条件
1: 97 percent / aq. NaHCO3 / tetrahydrofuran / 5 h / 25 °C 2: 1.) NaH / 1.) DMF, 25 deg C, 30 min, 2.) DMF, a) 0 deg C, 1 h, b) 25 deg C, overnight View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 4, # 5 p. 727 - 737
反应条件
dicobalt octacarbonyl; silica gel 1) ether, 19 h, 2) 70 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Becker, Daniel P.; Flynn, Daniel L.
Tetrahedron Letters, 1993 , vol. 34, # 13 p. 2087 - 2090
反应条件
oxygen; silica gel 1.) Et2O, r.t., 14-18 h, 2.) 70 deg C, 2.5 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Becker, Daniel P.; Flynn, Daniel L.
Tetrahedron Letters, 1993 , vol. 34, # 13 p. 2087 - 2090
