N-(1-甲基乙基)-2-(1-哌嗪)-3-氨基吡啶双盐酸盐水合物合成路线 (共 7 条)
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Romero; Morge; Biles; Berrios-Pena; May; Palmer; Johnson; Smith; Busso; Tan; Voorman; Reusser; Althaus; Downey; So; Resnick; Tarpley; Aristoff
Journal of Medicinal Chemistry, 1994 , vol. 37, # 7 p. 999 - 1014
反应条件
1: H2 / 10 percent Pd/C / methanol 2: NaCNBH3 / methanol 3: CF3COOH / CH2Cl2 View Scheme
参考文献
Arjomandi, Omid Khalili; Saemian, Nader; Shirvani, Gholamhossein; Javaheri, Mohsen; Esmailli, Kameh
Journal of Labelled Compounds and Radiopharmaceuticals, 2011 , vol. 54, # 7 p. 363 - 366
反应条件
1: CH2Cl2 2: H2 / Pd 3: NaCNBH3 4: TFA View Scheme
参考文献
Pinna; Loriga; Murineddu; Grella; Mura; Vargiu; Murgioni; La Colla
Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 11 p. 1406 - 1411
反应条件
1: Et3N / CH2Cl2 2: H2 / 10 percent Pd/C / methanol 3: NaCNBH3 / methanol 4: CF3COOH / CH2Cl2 View Scheme
参考文献
Pinna; Loriga; Murineddu; Grella; Mura; Vargiu; Murgioni; La Colla
Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 11 p. 1406 - 1411
反应条件
1: NaCNBH3 / methanol 2: CF3COOH / CH2Cl2 View Scheme
参考文献
Pinna; Loriga; Murineddu; Grella; Mura; Vargiu; Murgioni; La Colla
Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 11 p. 1406 - 1411
反应条件
trifluoroacetic acid
参考文献
Saemian, Nader; Shirvani, Gholamhossein; Matloubi, Hojatollah
Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 5-6 p. 576 - 577
反应条件
N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide
参考文献
Romero; Morge; Genin; Biles; Busso; Resnick; Althaus; Reusser; Thomas; Tarpley
Journal of Medicinal Chemistry, 1993 , vol. 36, # 10 p. 1505 - 1508