1: acetic acid 2: 92 percent / NaOCH3 / methanol / 24 h / Ambient temperature 3: 91 percent / K2CO3, copper, CuBr / dimethylformamide / 8 h / Heating 4: 80 percent / 2 h / Heating 5: 70 percent / acetone; H2O / 48 h / Ambient temperature View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4122945', constants.ctx, '0')">iron</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '506007', constants.ctx, '0')">acetic acid</a> <br />1&nbsp;h;&nbsp;&nbsp;Heating;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: pyridine / tetrahydrofuran / 2 h / Heating<br />2: iron, acetic acid / 1 h / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: pyridine / tetrahydrofuran / 2 h / Heating<br />2: iron, acetic acid / 1 h / Heating<br /> <br /> &nbsp;