顺-1,4-二氯-2-丁烯合成路线 （共 65 条）
反应条件
magnesium 1.) ether, 2.) reflux, 3 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 46, # 10 p. 2194 - 2196
反应条件
magnesium 1.) ether, 2.) reflux, 3 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Taylor, Stephen K.; Bennett, Stephen G.; Heinz, Karl J.; Lashley, Lauren K.
Journal of Organic Chemistry, 1981 , vol. 46, # 10 p. 2194 - 2196
反应条件
magnesium 1.) ether, 2.) reflux, 3 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Taylor, Stephen K.; Bennett, Stephen G.; Heinz, Karl J.; Lashley, Lauren K.
Journal of Organic Chemistry, 1981 , vol. 46, # 10 p. 2194 - 2196
反应条件
tetrahydrofuran; sodium hydroxide
参考文献
Reppe et al.
Justus Liebigs Annalen der Chemie, 1955 , vol. 596, p. 1,132
反应条件
in benzene byproducts: CHCHCH2CH2PC6H2(C4H9)3, P(CH3)3; (N2);
参考文献
Breen, Tricia L.; Stephan, Douglas W.
Journal of the American Chemical Society, 1995 , vol. 117, # 48 p. 11914 - 11921
反应条件
potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in dichloromethane T=30 - 35°C; 0.5 h;
参考文献
Menchikov, L. G.; D'yachenko, A. I.; Nefedov, O. M.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1985 , vol. 34, # 4 p. 867 - 868
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1985 , # 4 p. 949 - 950
反应条件
Grubb's 2nd generation catalyst in dichloromethane Heating;
参考文献
Scholte, Andrew A.; Mi, Hyun An; Snapper, Marc L.
Organic Letters, 2006 , vol. 8, # 21 p. 4759 - 4762
反应条件
potassium hydroxide 2.) 25 deg C, 4 h, 3.) reflux, 3 days; Yield given. Multistep reaction;
参考文献
Wilson, Stephen R.; Wiesler, Donald P.
Synthetic Communications, 1980 , vol. 10, # 4 p. 339 - 344
反应条件
1: malonic acid dimethyl ester With lithium hydride in N,N-dimethyl-formamide T=0°C; 4 h; 2: (Z)-1,4-Dichloro-2-butene in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
Broggi, Julie; Joubert, Nicolas; Diez-Gonzalez, Silvia; Berteina-Raboin, Sabine; Zevaco, Thomas; Nolan, Steven P.; Agrofoglio, Luigi A.
Tetrahedron, 2009 , vol. 65, # 6 p. 1162 - 1170
参考文献
Curators of the University of Missouri; 3M Innovative Properties Company
Patent: US6458865 B2, 2002 ;
