顺-1,4-二氯-2-丁烯合成路线 （共 65 条）
反应条件
1: benzenesulfonamide With sodium hydride in N,N-dimethyl-formamide T=20°C; 0.166667 h; 2: (Z)-1,4-Dichloro-2-butene in N,N-dimethyl-formamide T=20°C; 20 h;
参考文献
Laboratorios del Dr. Esteve S.A.
Patent: EP1849781 A1, 2007 ;
Location in patent: Page/Page column 89 ;
反应条件
4,4'-di-tert-butylbiphenyl; lithium in tetrahydrofuran T=0°C; 0.75 h; Yield given. Yields of byproduct given;
参考文献
Guijarro, Albert; Yus, Miguel
Tetrahedron, 1994 , vol. 50, # 26 p. 7857 - 7864
反应条件
in various solvent(s) Ambient temperatureelectrolysis (Bu4NBF4/Bu4NI, Al anode, steel cathode);
参考文献
Lu, Yu-Wei; Nedelec, Jean-Yves; Folest, Jean-Claude; Perichon, Jacques
Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2503 - 2507
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride
T=25°C; 14 h; Yield given. Yields of byproduct given;
参考文献
Depres, Jean-Pierre; Greene, Andrew E.
Journal of Organic Chemistry, 1984 , vol. 49, # 5 p. 928 - 931
反应条件
4,4'-di-tert-butylbiphenyl; lithium in tetrahydrofuran
T=0°C; 0.75 h;
参考文献
Guijarro, Albert; Yus, Miguel
Tetrahedron, 1994 , vol. 50, # 26 p. 7857 - 7864
反应条件
lithium hydride in N,N-dimethyl-formamide
multistep react.; other bases, solvents, reaction times; other substrates; Product distribution;
参考文献
Depres, Jean-Pierre; Greene, Andrew E.
Journal of Organic Chemistry, 1984 , vol. 49, # 5 p. 928 - 931
反应条件
N-ethyl-N,N-diisopropylamine in toluene
Heating;
参考文献
Nijhuis, W. H. N.; Verboom, W.; Harkema, S.; Reinhoudt, D. N.
Recueil des Travaux Chimiques des Pays-Bas, 1989 , vol. 108, # 4 p. 147 - 160
反应条件
Yield given. Multistep reaction;
参考文献
Bashore, Crystal G.; Vetelino, Michael G.; Wirtz, Michael C.; Brooks, Paige R.; Frost, Heather N.; McDermott, Ruth E.; Whritenour, David C.; Ragan, John A.; Rutherford, Jennifer L.; Makowski, Teresa W.; Brenek, Steven J.; Coe, Jotham W.
Organic Letters, 2006 , vol. 8, # 26 p. 5947 - 5950
反应条件
(i) NaOEt, (ii) aq. KOH; Multistep reaction;
参考文献
Murdock,K.C.; Angier,R.B.
Journal of Organic Chemistry, 1962 , vol. 27, p. 2395 - 2398
反应条件
lithium hydride
1) 1,2-dimethoxyethane, 5 h, 2) r.t., 72 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Depres, Jean-Pierre; Greene, Andrew E.
Journal of Organic Chemistry, 1984 , vol. 49, # 5 p. 928 - 931
