4-羟基-3-硝基苯磺酰氯合成路线 （共 4 条）
反应条件
chlorosulfonic acid T=60°C; 0.333333 h;
参考文献
Katritzky; Wu; Rachwal; Macomber; Smith
Synthetic Communications, 1993 , vol. 23, # 3 p. 405 - 417
反应条件
chlorosulfonic acid 1 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Synthetic Communications, , vol. 23, # 3 p. 405 - 417
反应条件
1: 4-(N,N-dimethlyamino)pyridine / tetrahydrofuran / 20 °C 2: ammonium formate / palladium on activated charcoal / ethanol / 20 - 80 °C View Scheme
参考文献
GLAXOSMITHKLINE LLC; KALLANDER, Lara, S.; LAWHORN, Brian, Griffin; PHILIP, Joanne; ZHAO, Yongdong
Patent: WO2011/88027 A1, 2011 ;
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran
T=20°C;
参考文献
GLAXOSMITHKLINE LLC; KALLANDER, Lara, S.; LAWHORN, Brian, Griffin; PHILIP, Joanne; ZHAO, Yongdong
Patent: WO2011/88027 A1, 2011 ;
Location in patent: Page/Page column 60 ;
