1: 95 percent / 10percent NaOH / 1 h / Heating 2: 80 percent / HCl / 4 h 3: 1.) 6N HCl, sodium nitrite / 1.) -10 deg C; 2.) dioxane, water, 80 deg C, 10 min 4: 85 percent / MnO2 / CH2Cl2 / Ambient temperature; 2-3 h 5: 1.) NaBH4; 2.) MnO2 / 1.) PdCl2(PPh)2 / 1.) methanol, 15 min; 2.) DCM, 30 min View Scheme

sodium hydroxide 1 h; Heating;