反应条件
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 3.5 h / 0 - 25 °C / |Inert atmosphere
1.2: 20 °C / |Inert atmosphere
2.1: lithium hexamethyldisilazane / tetrahydrofuran / -40 °C / |Inert atmosphere
2.2: -78 - 25 °C / |Inert atmosphere
3.1: palladium 10 on activated carbon; hydrogen / ethanol / 20 °C
View Scheme
参考文献
Gore, Vivek; Gravel, Sylvie; Cossette, Chantal; Patel, Pranav; Chourey, Shishir; Ye, Qiuji; Rokach, Joshua; Powell, William S.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 2 p. 364 - 377