7-甲基苯并[d]噻唑-2-胺合成路线 （共 4 条）
反应条件
iodine; oxygen; toluene-4-sulfonic acid in dimethyl sulfoxide T=75°C; P=760.051 Torr; 24 h; regioselective reaction;
参考文献
Zhao, Jinwu; Huang, Huawen; Wu, Wanqing; Chen, Huoji; Jiang, Huanfeng
Organic Letters, 2013 , vol. 15, # 11 p. 2604 - 2607
反应条件
1: With bromine in chloroform T=0 - 5°C; Reflux; 2: With ammonia in water
参考文献
Sharma, Pratibha; Kumar, Ashok; Kumari, Prerna; Singh, Jitendra; Kaushik
Medicinal Chemistry Research, 2012 , vol. 21, # 7 p. 1136 - 1148
参考文献
Desai; Mehta
Indian Journal of Pharmacy, 1951 , vol. 13, p. 208
Chem.Abstr., 1952 , p. 8626
反应条件
1.1: hydrogenchloride / water / 0.5 h / Reflux 1.2: 4 h / 20 °C / Reflux 2.1: bromine / chloroform / 0 - 5 °C / Reflux View Scheme
参考文献
Sharma, Pratibha; Kumar, Ashok; Kumari, Prerna; Singh, Jitendra; Kaushik
Medicinal Chemistry Research, 2012 , vol. 21, # 7 p. 1136 - 1148
