(2-氟苯甲酰)乙酸乙酯合成路线 （共 16 条）
反应条件
ammonium nitrate; bentonite in N,N-dimethyl-formamide 0.0833333 h; Irradiation;
参考文献
Cotterill, Ian C.; Usyatinsky, Alexander Ya.; Arnold, John M.; Clark, Douglas S.; Dordick, Jonathan S.; Michels, Peter C.; Khmelnitsky, Yuri L.
Tetrahedron Letters, 1998 , vol. 39, # 10 p. 1117 - 1120
反应条件
1.1: sodium nitrite; hydrogenchloride / water / 0.5 h / 0 °C
1.2: 0 °C
2.1: sodium hydroxide / ethanol; water / 2 h / 20 - 50 °C
View Scheme
参考文献
Li, Sai; Zhao, Yanfang; Wang, Kewen; Gao, Yali; Han, Jianming; Cui, Bingbing; Gong, Ping
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 11 p. 2843 - 2855
反应条件
1: ethanol; toluene / Heating
2: bromine / acetic acid / 3 h / Ambient temperature
View Scheme
参考文献
Skulnick; Weed; Eidson; Renis; Wierenga; Stringfellow
Journal of Medicinal Chemistry, 1985 , vol. 28, # 12 p. 1864 - 1869
反应条件
1: N,N-dimethyl-formamide / 0.5 h / 100 °C / Inert atmosphere
2: N,N-dimethyl-formamide / 48 h / 140 °C / Inert atmosphere
View Scheme
参考文献
Bunce, Richard A.; Lee, Eric J.; Grant, Matthew T.
Journal of Heterocyclic Chemistry, 2011 , vol. 48, # 3 p. 620 - 625
反应条件
ammonium nitrate; bentonite in N,N-dimethyl-formamide
0.0833333 h; Irradiation;
参考文献
Cotterill, Ian C.; Usyatinsky, Alexander Ya.; Arnold, John M.; Clark, Douglas S.; Dordick, Jonathan S.; Michels, Peter C.; Khmelnitsky, Yuri L.
Tetrahedron Letters, 1998 , vol. 39, # 10 p. 1117 - 1120
反应条件
(i) NaH, (ii) /BRN= 982281/; Multistep reaction;
参考文献
Coppola; Hardtmann
Journal of Heterocyclic Chemistry, 1979 , vol. 16, # 4 p. 829 - 830
