6-(氯甲酸基)己炔羧酸乙酯合成路线 （共 21 条）
反应条件
1: 1.) Zn-Cu 2: hydrolyze View Scheme
参考文献
Tahara, Satoshi; Hosokawa, Keizo; Mizutani, Junya
Agricultural and Biological Chemistry, 1980 , vol. 44, # 1 p. 193 - 198
反应条件
copper; zinc Multistep reaction;
参考文献
Tahara, Satoshi; Hosokawa, Keizo; Mizutani, Junya
Agricultural and Biological Chemistry, 1980 , vol. 44, # 1 p. 193 - 198
反应条件
1: AlCl3 / 2 h / 90 °C 2: NaBH4 / methanol / 0.5 h / 0 °C 3: 95 percent / 2.5 N NaOH / tetrahydrofuran / 3 h / 70 °C View Scheme
参考文献
Shiraishi; Kato; Terao; Ashida; Terashita; Kito
Journal of Medicinal Chemistry, 1989 , vol. 32, # 9 p. 2214 - 2221
参考文献
Brockman; Fabio
Journal of the American Chemical Society, 1957 , vol. 79, p. 5027
反应条件
1: AlCl3 / 2 h / 90 °C 2: NaBH4 / methanol / 0.5 h / 0 °C 3: 95 percent / 2.5 N NaOH / tetrahydrofuran / 3 h / 70 °C 4: boron trifluoride etherate / toluene / 2 h / 60 °C 5: aq. FeCl3 / tetrahydrofuran / 0.5 h / Ambient temperature View Scheme
参考文献
Shiraishi; Kato; Terao; Ashida; Terashita; Kito
Journal of Medicinal Chemistry, 1989 , vol. 32, # 9 p. 2214 - 2221
反应条件
aluminium trichloride T=90°C; 2 h;
参考文献
Shiraishi; Kato; Terao; Ashida; Terashita; Kito
Journal of Medicinal Chemistry, 1989 , vol. 32, # 9 p. 2214 - 2221
反应条件
aluminium trichloride T=20°C; Friedel-Crafts reaction;
参考文献
Maekawa, Tsuyoshi; Sakai, Nozomu; Tawada, Hiroyuki; Murase, Katsuhito; Hazama, Masatoshi; Sugiyama, Yasuo; Momose
Chemical and pharmaceutical bulletin, 2003 , vol. 51, # 5 p. 565 - 573
反应条件
aluminium trichloride in 1,2-dichloro-ethane
参考文献
Labaudiniere, Richard; Hilboll, Gerd; Leon-Lomeli, Alicia; Lautenschlaeger, Hans-Heiner; Parnham, Michael; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3156 - 3169
参考文献
Robinson
Journal of the Chemical Society, 1930 , p. 749
参考文献
Bayer AG
Patent: DE2515146 , 1976 ;
Chem.Abstr., 1977 , vol. 86, # 71947
