1: With N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=-40 - 25°C; 1 h; 2: With 4-methyl-morpholine; hydrogen; acetic acid; palladium on activated carbon in water; ethyl acetate; N,N-dimethyl-formamide T=25°C; pH=6.5 - 7.0; 3 h;