4-溴-2,6-二甲基苯甲醚合成路线 （共 24 条）
反应条件
bromine in various solvent(s) Irradiationirrad., 1,2-dibromoethane, reflux, 1 h;
参考文献
Tashiro, Masashi; Mataka, Shuntaro; Takezaki, Yoshinori; Takeshita, Michinori; Arimura, Takashi; et al.
Journal of Organic Chemistry, 1989 , vol. 54, # 2 p. 451 - 458
反应条件
(i), (ii) (saponification); Multistep reaction;
参考文献
Mijs,W.J. et al.
Tetrahedron, 1967 , vol. 23, p. 2253 - 2264
反应条件
triphenylphosphine; nickel dichloride; zinc in N,N-dimethyl-formamide
T=50 - 60°C; 12 h;
参考文献
Yamato, Takehiko; Hideshima, Chieko; Suehiro, Kazuaki; Tashiro, Masashi; Prakash, G. K. Surya; Olah, George A.
Journal of Organic Chemistry, 1991 , vol. 56, # 21 p. 6248 - 6250
反应条件
1: With tert.-butyl lithium in diethyl ether; hexane
T=-78°C; 1 h; Inert atmosphere;
2: With iodine in diethyl ether; hexane
T=-78 - 20°C; 2 h; Inert atmosphere;
参考文献
Zhao, Wenjun; Huang, Li; Guan, Yong; Wulff, William D.
Angewandte Chemie - International Edition, 2014 , vol. 53, # 13 p. 3436 - 3441
Angew. Chem., 2014 , vol. 126, # 13 p. 3504 - 3509,6
