1,3,5-三(9-咔唑基)苯合成路线 (共 2 条)
反应条件
cBRIDP; bis(η3-allyl-μ-chloropalladium(II)); methyl-magnesium chloride in tetrahydrofuran; anhydrous xylene T=5°C; Buchwald-Hartwig Coupling; Inert atmosphereReflux;
参考文献
TAKASAGO INTERNATIONAL CORPORATION; NAKAYAMA, Yuji; KOBAYASHI, Tohru
Patent: WO2013/32035 A1, 2013 ;
Location in patent: Page/Page column 45; 46 ;
反应条件
copper(l) iodide; 1,10-phenanthroline; potassium carbonate in N,N-dimethyl-formamide T=20 - 110°C; 72.5 h; Inert atmosphere;
参考文献
Chen, Qi; Luo, Min; Hammershoj; Zhou, Ding; Han, Ying; Laursen, Bo Wegge; Yan, Chao-Guo; Han, Bao-Hang
Journal of the American Chemical Society, 2012 , vol. 134, # 14 p. 6084 - 6087