4-(4-甲基哌嗪甲基)苯甲酰氯合成路线 (共 3 条)
反应条件
thionyl chloride; N,N-dimethyl-formamide in 1,2-dichloro-ethane T=80°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 1 p. 193 - 196
反应条件
triethylamine in dichloromethane T=0 - 30°C; 10 h; Product distribution / selectivity;
参考文献
WO2008/98949 A2, ;
Page/Page column 21-22 ;
WO 2008/098949 A2
反应条件
pyridine T=50°C; 4.5 h;
参考文献
CHEMAGIS LTD.
Patent: EP1857454 A1, 2007 ;
Location in patent: Page/Page column 4 ;