11-乙氧羰基十二烷酰氯合成路线 （共 10 条）
反应条件
thionyl chloride 4 h; Heating;
参考文献
Zakharkin, L. I.; Guseva, V. V.; Churilova, I. M.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, p. 1632 - 1634
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 9 p. 1866 - 1869
反应条件
1: 58 percent / conc. H2SO4 / cyclohexane / 48 h 2: SOCl2 / benzene / 1 h / Heating View Scheme
参考文献
Menger, F. M.; Wood, M. G.; Richardson, S.; Zhou, Q.; Elrington, A. R.; Sherrod, M. J.
Journal of the American Chemical Society, 1988 , vol. 110, # 20 p. 6797 - 6803
反应条件
triethylamine in tetrahydrofuran T=0°C;
参考文献
Zhang, Xiao-Xiang; Prata, Carla A. H.; Berlin, Jason A.; McIntosh, Thomas J.; Barthelemy, Philippe; Grinstaff, Mark W.
Bioconjugate Chemistry, 2011 , vol. 22, # 4 p. 690 - 699
反应条件
Pd-BaSO4; xylene Hydrogenation;
参考文献
Sobotka; Stynler
Journal of the American Chemical Society, 1950 , vol. 72, p. 5139,5141
反应条件
1: 1) Mg / 1) THF, -78 gradC, 1.5 h; 2) raised to 20 gradC 2: 91 percent / H2 / Raney nickel / ethanol / 15 h / 150 °C 3: 96 percent / NaOH / aq. ethanol / 6 h / Heating View Scheme
参考文献
Zakharkin, L. I.; Guseva, V. V.; Churilova, I. M.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, p. 1632 - 1634
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 9 p. 1866 - 1869
反应条件
1: Friedel-Crafts reaction
2: Wolff-Kishner reduction
View Scheme
参考文献
Ouchi, Akihiko; Niino, Hiroyuki; Kawabata, Yasujiro; Tanaka, Motoo; Yabe, Akira
Tetrahedron Letters, 1990 , vol. 31, # 42 p. 6043 - 6046
反应条件
1: 1) Mg / 1) THF, -78 gradC, 1.5 h; 2) raised to 20 gradC
2: 91 percent / H2 / Raney nickel / ethanol / 15 h / 150 °C
View Scheme
参考文献
Zakharkin, L. I.; Guseva, V. V.; Churilova, I. M.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, p. 1632 - 1634
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 9 p. 1866 - 1869
参考文献
Jones
Journal of the American Chemical Society, 1947 , vol. 69, p. 2352
反应条件
sulfuric acid in benzene
参考文献
Menger, F. M.; Wood, M. G.; Richardson, S.; Zhou, Q.; Elrington, A. R.; Sherrod, M. J.
Journal of the American Chemical Society, 1988 , vol. 110, # 20 p. 6797 - 6803
反应条件
magnesium
1) THF, -78 gradC, 1.5 h; 2) raised to 20 gradC; Yield given. Multistep reaction;
参考文献
Zakharkin, L. I.; Guseva, V. V.; Churilova, I. M.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, p. 1632 - 1634
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 9 p. 1866 - 1869
