3-溴-1-(三异丙基甲硅烷基)吲哚合成路线 （共 15 条）
反应条件
1: With N,N,N',N,-tetramethylethylenediamine; tert.-butyl lithium in hexane; pentane T=0°C; 3 h; 2: With 1,2-dibromo-1,1,2,2-tetrafluoroethane in diethyl ether T=-78°C; 1 h;
参考文献
Matsuzono, Mai; Fukuda, Tsutomu; Iwao, Masatomo
Tetrahedron Letters, 2001 , vol. 42, # 43 p. 7621 - 7623
反应条件
N-bromosuccinmide in dichloromethane T=20°C; retro-Mannich fragmentation; 0.0333333 h;
参考文献
Chauder, Brian; Larkin, Andrew; Snieckus, Victor
Organic letters, 2002 , vol. 4, # 5 p. 815 - 817
反应条件
1: 98 percent / n-BuLi / tetrahydrofuran / -78 °C 2: NBS / tetrahydrofuran / -78 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 21 p. 3455 - 3458
反应条件
1: 1.) NaH / 1.) DMF, 2.) DMF, overnight 2: 89 percent / pyridinium bromide perbromide / pyridine / 0 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 115, # 9 p. 3499 - 3502
反应条件
N-bromosuccinmide in tetrahydrofuran T=-78°C; Yield given. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 39, # 21 p. 3455 - 3458
反应条件
1: tert-BuLi / pentane; tetrahydrofuran / 0.17 h / -78 °C 2: pentane; tetrahydrofuran / 0.25 h / -78 °C 3: TBAF / tetrahydrofuran / 0.17 h / 25 °C View Scheme
参考文献
Amat, Mercedes; Sathyanarayana, Swargam; Hadida, Sabine; Bosch, Joan
Heterocycles, 1996 , vol. 43, # 8 p. 1713 - 1718
反应条件
1: tert-BuLi / pentane; tetrahydrofuran / 0.17 h / -78 °C 2: pentane; tetrahydrofuran / 0.25 h / -78 °C 3: TBAF / tetrahydrofuran / 0.17 h / 25 °C View Scheme
参考文献
Amat, Mercedes; Sathyanarayana, Swargam; Hadida, Sabine; Bosch, Joan
Heterocycles, 1996 , vol. 43, # 8 p. 1713 - 1718
反应条件
1: tert-BuLi / pentane; tetrahydrofuran / 0.17 h / -78 °C 2: pentane; tetrahydrofuran / 0.25 h / -78 °C 3: TBAF / tetrahydrofuran / 0.17 h / 25 °C View Scheme
参考文献
Amat, Mercedes; Sathyanarayana, Swargam; Hadida, Sabine; Bosch, Joan
Heterocycles, 1996 , vol. 43, # 8 p. 1713 - 1718
反应条件
1: tert-BuLi / pentane; tetrahydrofuran / 0.17 h / -78 °C 2: pentane; tetrahydrofuran / 0.25 h / -78 °C 3: TBAF / tetrahydrofuran / 0.17 h / 25 °C View Scheme
参考文献
Amat, Mercedes; Sathyanarayana, Swargam; Hadida, Sabine; Bosch, Joan
Heterocycles, 1996 , vol. 43, # 8 p. 1713 - 1718
反应条件
3,3-dimethylbut-1-ene; RhCl(CO)(PFur3)2; caesium carbonate in 1,4-dioxane T=120°C; 14 h;
参考文献
Sezen, Bengue; Sames, Dalibor
Journal of the American Chemical Society, 2004 , vol. 126, # 41 p. 13244 - 13246
