3-溴-1-(三异丙基甲硅烷基)吲哚合成路线 （共 15 条）
反应条件
1: 3-bromo-1-(1,1,1-triisopropylsilyl)-1H-indole With tert.-butyl lithium in tetrahydrofuran; pentane T=-78°C; 0.333333 h; 2: tert-nitrodienamine in tetrahydrofuran; pentane T=-78 - 20°C;
参考文献
Heterocycles, , vol. 53, # 12 p. 2701 - 2708
反应条件
1.1: tBuLi / tetrahydrofuran 1.2: B(OiPr)3 / tetrahydrofuran 1.3: 86 percent / LiOH; aq. Na2CO3; Pd(PPh3)4 / tetrahydrofuran / 20 °C 2.1: tetrabutylammonium fluoride View Scheme
参考文献
Nishida, Atsushi; Miyashita, Naoki; Fuwa, Mihoko; Nakagawa, Masako
Heterocycles, 2003 , vol. 59, # 2 p. 473 - 476
反应条件
1: cesium carbonate; tri(tert-butyl)phosphonium tetrafluoroborate / Pd(dba)2 / tetrahydrofuran / 18 h / Heating 2: 1.74 g / tetrabutylammonium fluoride / tetrahydrofuran / 1.17 h / 0 - 20 °C View Scheme
参考文献
Kuwano, Ryoichi; Kashiwabara, Manabu; Sato, Koji; Ito, Takashi; Kaneda, Kohei; Ito, Yoshihiko
Tetrahedron Asymmetry, 2006 , vol. 17, # 4 p. 521 - 535
反应条件
1: tert-BuLi / pentane; tetrahydrofuran / 0.17 h / -78 °C
2: pentane; tetrahydrofuran / 0.25 h / -78 °C
3: TBAF / tetrahydrofuran / 0.17 h / 25 °C
View Scheme
参考文献
Amat, Mercedes; Sathyanarayana, Swargam; Hadida, Sabine; Bosch, Joan
Heterocycles, 1996 , vol. 43, # 8 p. 1713 - 1718
反应条件
1: tert-BuLi / pentane; tetrahydrofuran / 0.17 h / -78 °C
2: pentane; tetrahydrofuran / 0.25 h / -78 °C
3: TBAF / tetrahydrofuran / 0.17 h / 25 °C
View Scheme
参考文献
Amat, Mercedes; Sathyanarayana, Swargam; Hadida, Sabine; Bosch, Joan
Heterocycles, 1996 , vol. 43, # 8 p. 1713 - 1718
