3-(2H-四唑-5-基)苯甲酸甲酯合成路线 （共 4 条）
反应条件
sodium azide; ammonium chloride in N,N-dimethyl-formamide T=120°C; 2.5 h;
参考文献
Tanaka, Akira; Terasawa, Takeshi; Hagihara, Hiroyuki; Sakuma, Yuri; Ishibe, Noriko; Sawada, Masae; Takasugi, Hisashi; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 1998 , vol. 41, # 13 p. 2390 - 2410
反应条件
1: POCl3, DMF / ethyl acetate / 0.5 h / 5 °C 2: ethyl acetate / 18 h / Ambient temperature 3: 99 percent / NaN3, NH4Cl / dimethylformamide / 2.5 h / 120 °C View Scheme
参考文献
Tanaka, Akira; Terasawa, Takeshi; Hagihara, Hiroyuki; Sakuma, Yuri; Ishibe, Noriko; Sawada, Masae; Takasugi, Hisashi; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 1998 , vol. 41, # 13 p. 2390 - 2410
反应条件
1: ethyl acetate / 18 h / Ambient temperature 2: 99 percent / NaN3, NH4Cl / dimethylformamide / 2.5 h / 120 °C View Scheme
参考文献
Tanaka, Akira; Terasawa, Takeshi; Hagihara, Hiroyuki; Sakuma, Yuri; Ishibe, Noriko; Sawada, Masae; Takasugi, Hisashi; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 1998 , vol. 41, # 13 p. 2390 - 2410
反应条件
sodium hydroxide in methanol; water Inert atmosphere;
参考文献
Aiello, Francesca; Shabaik, Yumna; Esqueda, Adrian; Sanchez, Tino W.; Grande, Fedora; Garofalo, Antonio; Neamati, Nouri
ChemMedChem, 2012 , vol. 7, # 10 p. 1825 - 1839
