反应条件
1: 1.) n-butyllithium / 1.) THF, 1h, -78 deg C to 0 deg C, 2.) -78 deg C to room temp.
2: 1.) phenyllithium / 1a) THF, -78 deg C, 15min; 1b) up to room temp.; 1c) room. temp., 45min; 2.) 2h, -78 deg C to room temp.
3: 90 percent / activated MnO2 / CH2Cl2 / 16 h / Heating
4: 100 percent / N-bromosuccinimide / benzoyl peroxide / CCl4 / 2.5 h / Heating
5: 96 percent / H2O, sodium bicarbonate / tetrahydrofuran / 22.5 h
6: 99 percent / hexane; CH2Cl2 / 0.75 h / Heating
View Scheme
参考文献
Gribble, Gordon W.; Saulnier, Mark G.; Sibi, Mukund P.; Obaza-Nutaitis, Judy A.
Journal of Organic Chemistry, 1984 , vol. 49, # 23 p. 4518 - 4523
