4-(5-氨基-2-甲氧基苯基)哌嗪-1-羧酸叔丁酯合成路线 （共 3 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol 18 h; Ambient temperature;
参考文献
Bromidge, Steven M.; Brown, Anthony M.; Clarke, Stephen E.; Dodgson, Kathy; Gager, Tracey; Grassam, Helen L.; Jeffrey, Phil M.; Joiner, Graham F.; King, Frank D.; Middlemiss, Derek N.; Moss, Stephen F.; Newman, Helen; Riley, Graham; Routledge, Carol; Wyman, Paul
Journal of Medicinal Chemistry, 1999 , vol. 42, # 2 p. 202 - 205
反应条件
1: 89 percent / K2CO3 / tetrahydrofuran; H2O / 18 h / Ambient temperature 2: 99 percent / H2 / 10 percent Pd/C / ethanol / 18 h / Ambient temperature View Scheme
参考文献
Bromidge, Steven M.; Brown, Anthony M.; Clarke, Stephen E.; Dodgson, Kathy; Gager, Tracey; Grassam, Helen L.; Jeffrey, Phil M.; Joiner, Graham F.; King, Frank D.; Middlemiss, Derek N.; Moss, Stephen F.; Newman, Helen; Riley, Graham; Routledge, Carol; Wyman, Paul
Journal of Medicinal Chemistry, 1999 , vol. 42, # 2 p. 202 - 205
反应条件
1: 89 percent / K2CO3 / tetrahydrofuran; H2O / 18 h / Ambient temperature 2: 99 percent / H2 / 10 percent Pd/C / ethanol / 18 h / Ambient temperature View Scheme
参考文献
Bromidge, Steven M.; Brown, Anthony M.; Clarke, Stephen E.; Dodgson, Kathy; Gager, Tracey; Grassam, Helen L.; Jeffrey, Phil M.; Joiner, Graham F.; King, Frank D.; Middlemiss, Derek N.; Moss, Stephen F.; Newman, Helen; Riley, Graham; Routledge, Carol; Wyman, Paul
Journal of Medicinal Chemistry, 1999 , vol. 42, # 2 p. 202 - 205
