3,4-二(苄氧基)苯甲酰氯合成路线 （共 14 条）
反应条件
thionyl chloride; N,N-dimethyl-formamide 6 h; Heating;
参考文献
Boers, Frank; Deng, Bo-Liang; Lemiere, Guy; Lepoivre, Jozef; De Groot, Alex; Dommisse, Roger; Vlietinck, Arnold J.
Archiv der Pharmazie, 1997 , vol. 330, # 9-10 p. 313 - 316
反应条件
1: 93 percent / Jones reagent / acetone / 2 h / Ambient temperature 2: oxalyl chloride, DMF / CH2Cl2 / 2 h / Ambient temperature View Scheme
参考文献
Boers, Frank; Deng, Bo-Liang; Lemiere, Guy; Lepoivre, Jozef; De Groot, Alex; Dommisse, Roger; Vlietinck, Arnold J.
Archiv der Pharmazie, 1997 , vol. 330, # 9-10 p. 313 - 316
反应条件
1: K2CO3*1.5H2O / acetone / 24 h / Heating 2: 1.93 g / NaOH / H2O; methanol / 3 h / Heating 3: oxalyl chloride; DMF / hexane; CH2Cl2 / 3 h / 0 °C View Scheme
参考文献
Gardner, Richard Andrew; Kinkade, Rebecca; Wang, Chaojie; Phanstiel IV, Otto
Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3530 - 3537
反应条件
1: K2CO3*1.5H2O / acetone / 24 h / Heating 2: 1.93 g / NaOH / H2O; methanol / 3 h / Heating 3: oxalyl chloride; DMF / hexane; CH2Cl2 / 3 h / 0 °C View Scheme
参考文献
Gardner, Richard Andrew; Kinkade, Rebecca; Wang, Chaojie; Phanstiel IV, Otto
Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3530 - 3537
反应条件
1: 1.93 g / NaOH / H2O; methanol / 3 h / Heating 2: oxalyl chloride; DMF / hexane; CH2Cl2 / 3 h / 0 °C View Scheme
参考文献
Gardner, Richard Andrew; Kinkade, Rebecca; Wang, Chaojie; Phanstiel IV, Otto
Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3530 - 3537
反应条件
2: SOCl2 View Scheme
参考文献
Neish
Canadian Journal of Biochemistry and Physiology, 1959 , vol. 37, p. 1439,1442
反应条件
2: SOCl2 View Scheme
参考文献
Neish
Canadian Journal of Biochemistry and Physiology, 1959 , vol. 37, p. 1439,1442
反应条件
quinoline; Pd-BaSO4; sulfur Hydrogenation.Reagens 4: Xylol;
参考文献
Neish
Canadian Journal of Biochemistry and Physiology, 1959 , vol. 37, p. 1439,1442
反应条件
1: pyridine / 3 h / 120 °C 2: KOH, pyridine / 4 h / 60 °C 3: 88 percent / AcONa, AcOH / 3 h / 140 - 145 °C 4: 97 percent / H2 / 10percent Pd/C / methanol; ethyl acetate 5: pyridine / Heating 6: AlCl3 / acetonitrile / 1.5 h / 60 °C 7: 6 M HCl / methanol / 4 h / Heating View Scheme
参考文献
Horie, Tokunaru; Tsukayama, Masao; Kourai, Hiroki; Yokoyama, Chieko; Furukawa, Masayuki; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2256 - 2262
反应条件
1: 60 percent / pyridine / diethyl ether / 24 h / 0 °C 2: 1) potassium 3,4-dibenzyloxybenzoate, 2) aq. KOH / 1) 160 deg C, 8 h, 2) MeOH, reflux 3: 99 percent / cyclohexene / Pd(OH)2/C / ethanol / 0.5 h / Heating View Scheme
参考文献
Boers, Frank; Deng, Bo-Liang; Lemiere, Guy; Lepoivre, Jozef; De Groot, Alex; Dommisse, Roger; Vlietinck, Arnold J.
Archiv der Pharmazie, 1997 , vol. 330, # 9-10 p. 313 - 316
